According to a recent study published in New England Journal of Medicine, teens and youngsters that have attention deficit hyperactivity disorder or ADHD are under greater risk of psychosis if they receive amphetamines when compared to those that receive methyphenidates based stimulants like Ritalin. The study’s authors examined databases of two large national level insurance claims and then followed 221486 these youngsters in the age group of 13 to mid-20’s that had mild ADHD and were given a stimulant for the first time between years 2004 and 2015. This study group was divided into two groups one of which was given amphetamine based Adderall and another half was given methylphenidates like Ritalin
Of the 343 youngsters that were being examined it was discovered that one of every group of 660 people developed psychosis during first few months of after starting the stimulant. This is a risky experiment as its risk of serious side effect was large at 0.21 percent for patients that took amphetamine when compared to those taking methylphenidate as per recent results. Dr. Lauren Moran, assistant professor and lead author of this study stated that people even without any psychiatric history develop episodes of psychosis during use of simulants particularly Adderall.
She said that her experience of caring for youngsters with psychosis prompted her team to carry out this research. ADHD is a disorder that is symptomized by lack of attention, hyperactivity and restlessness that could be frequent on severe depending on the individual’s condition. Earlier stimulants were considered as the most effective drugs to control these symptoms but since 2007 FDA has asked manufacturers to add a warning that these could cause psychotic or manic symptoms in people that have never had such issues in the past. Dr. Lauren Moran stated that her team focused on youngsters that were taking stimulants for the first time and emphasized that risk for people that have been taking it for a long time is lower.