Mayo Clinic Researchers Identify Gene Predicting Pancreatic Cancer Risk
Researchers at Mayo Clinic proclaimed that they have found a novel gene. The newly discovered gene named “UCP-1” might predict the growth of pancreatic cancer in individuals with Type 2 diabetes. The findings of this research can be accessed in the journal Gastroenterology.
Suresh Chari, M.D., Gastroenterologist, Mayo Clinic, is the senior author of this research. He proclaimed that developing plans for the early detection of pancreatic cancer in individuals with no symptoms is a key to improve the survival rate. For this research, Dr. Chari and his associates studied a group of patients suffering from pancreatic cancer. These patients were matched with controls. Researchers reviewed alterations in patients’ body weight, fasting blood glucose, and blood lipids over a 5-year period before their pancreatic cancer diagnosis. At the same time, they also studied a series of CT scans completed over time for other suggestions before their diagnosis.
On a similar note, a novel study, published in the Journal of Clinical Investigation, highlighted that epinephrine, the stress hormone, sets off a drop in biochemical reactions, which help in the growth and spread of breast cancer. In this study, the scientists initially revealed the effects of persistent stress on cancer stem cell development. This is said to be a new twist on earlier research that did not particularly aim at these self-perpetuating cells.
Keith Kelley, Emeritus Professor, Department of Animal Sciences and the College of Medicine, University of Illinois, is the author of this study. He stated that all the cells in a tumor can be killed. However, if the mother cells or stem cells are not killed, then the tumor will develop and metastasize again. Reportedly, this is one of the foremost studies to associate chronic stress particularly with the development of breast cancer stem cells.