Research Reveals Leaky Blood Vessels Linked To Alzheimer’s
Since the total numbers of patients affected with Alzheimer’s disease are increasing at an exponential rate, the researchers are not leaving any stone unturned to find a way to prevent the same. Every year, a form of Alzheimer’s disease, dementia, affects over 50 million people across the globe. Also, 5 million people are suffering from this ailment in the US, which may become 14 million by the end of 2050. Hence, the researchers are executing several experiments to get proper control over the same. In the latest research, it was proved that the leaking blood vessels may have a direct link with Alzheimer’s disease.
The scientists have also stated that it is crucial to identifying the ailment in the preliminary stage that will allow them to slow down the effect of the same with the help of certain drugs and therapies. Currently, the FDA or Food & Drug Administration has sanctioned a few drugs that have the potential to treat the concerns of Alzheimer’s disease. However, these have failed to treat the causes leading to the ailment.
In the last few studies, tau and amyloid were declared as two such toxic proteins that trigger the development of the factors that lead to the formation of Alzheimer’s disease. In fact, the soluble form of these two toxins operates to harm the well-functioning neurons. However, this research came under a new light after being proved that the people who are having the most severe memory concerns have the history of leaky capillaries, whether or not their healthy neurons were attacked by the team of toxins.
In the human brain, a structure is formed called the blood-brain barrier that makes up the blood vessels. For a healthy human being, this barrier is so strong that it tightly knits the cells together, resisting the other substances from getting in. However, aging weakens the barrier, allowing unwanted elements to enter the brain and resulting in Alzheimer’s disease.